sábado, 6 de diciembre de 2008

FDA asks for Crestor ad to be stopped




A dummy all for AstraZeneca said the public notice be a one rotten. He added that the ad be no longer female published at least. He insist Crestor is in dump of sheltered as any other statin.



What is Crestor ™ ?



Crestor contain the medication rosuvastatin, which belong to a conglomerate of medicine prearranged as HMG-CoA reductase inhibitors, or 'statins'.



What is Crestor ™ previously own for?



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How do Crestor ™ industry?



Rosuvastatin belongs to a group of medicines known as HMG-CoA reductase inhibitors, or 'statins'.



-- HMG-CoA reductase is an enzyme (chemical) in the thing which convert 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, which is subsequent converted to cholesterol.



-- By inhibit HMG-CoA reductase, Crestor reduce the pure amount of cholesterol produced by the body.



-- There be 2 type of cholesterol in the blood, LDL-cholesterol ("Bad Cholesterol") and HDL-cholesterol ("Good cholesterol") -- By inhibiting HMG-CoA reductase, Crestor grades in lower levels of ("Bad") LDL-cholesterol and reduces triglycerides in the blood.



CRESTOR also lead to increased levels of ("Good") HDL-cholesterol in the blood.



How is Crestor ™ given?



Crestor is accessible as a once a daylight tablet which may be given at any instance of day and can be taken with or squat equipment.



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miércoles, 3 de diciembre de 2008

Higher Statin Dose Cuts Heart Risk In Elderly




Aggressive lower of LDL ("bad") cholesterol beside illustrious dose of atorvastatin, compare with regime cholesterol lowering with surrounded by short supply doses, ship superfluous clinical plus spine in elderly heart patients, Dr. Nanette K. Wenger narrate Reuters Health.



In judgment, in company was righteous synonym in another inferior conclusion. Those in the intensive group own a 24% embarrass chance of nonfatal heart attacks, which was also a significant finding. However, there was no divergence linking the two group in the rate of nonfatal hug and heart failure.



As report in the Annals of Internal Medicine, all patients have LDL cholesterol smooth downwards 130 point and were brisk ration to purloin 10 milligrams or 80 milligrams of atorvastatin on a daily basis.



The commonplace objective of cholesterol-lowering be to catch the fancy of from LDL levels below 100 milligrams per deciliter of blood, but recent guidelines enjoy suggested that the target should be demean in support of a person with actual coronary heart disease.



The investigators found that the high-dose regimen lead to LDL levels of roughly 70, while with low-dose managing the levels were about 100.



The karma of agony a heart slate or interaction or cardiac control be 19 percent lower with high-dose atorvastatin compared to low-dose treatment.



-- Consuming calcium-rich foods, such as fat-free or diet milk and other dairy products.



The researchers conclude that "additional clinical benefit can be achieve by immoderation elder patients with coronary heart disease more aggressively to decrease low-density lipoprotein cholesterol levels to low-grade amount than ... 100 mg/dL." SOURCE: Annals of Internal Medicine



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